1 article featuring Ocimene
Depression is often a systemic physiological state. It disrupts sleep architecture, metabolic recovery, and executive function. Emerging research explores Clinical Endocannabinoid Deficiency (CECD) as a factor in these states. This theory suggests the body may lack the basal tone of endocannabinoids—specifically anandamide (AEA) and 2-arachidonoylglycerol (2-AG)—needed to regulate the stress response and maintain homeostasis.